Single‐cell RNA‐seq reveals the invasive trajectory and molecular cascades underlying glioblastoma progression
Glioblastoma (GBM) is the most common and aggressive primary brain tumor, in which GBM stem cells (GSCs) were identified to contribute to aggressive phenotypes and poor prognosis. Yet, how GSCs progress to invasive cells remains largely unexplored. Here, we revealed the cell subpopulations with dist...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-12-01
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Series: | Molecular Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/1878-0261.12569 |