The role of cells and signal pathways in subchondral bone in osteoarthritis

Osteoarthritis (OA) is mainly caused by ageing, strain, trauma, and congenital joint abnormalities, resulting in articular cartilage degeneration. During the pathogenesis of OA, the changes in subchondral bone (SB) are not only secondary manifestations of OA, but also an active part of the disease,...

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Bibliographic Details
Main Authors: Pan Luo, Qi-ling Yuan, Mingyi Yang, Xianjie Wan, Peng Xu
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2023-09-01
Series:Bone & Joint Research
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.129.BJR-2023-0081.R1