A Preconditioning Regimen with a PKCε Activator Improves Islet Graft Function in a Mouse Transplant Model
Transplantation of islets isolated from deceased donor pancreata is an attractive method of β-cell replacement therapy for patients with type 1 diabetes (T1D). However, the loss of islet cell viability and function during the peritransplant period is a limiting factor to long-term islet engraftment....
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-07-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368913X665567 |