Involvement of endothelial CK2 in the radiation induced perivascular resistant niche (PVRN) and the induction of radioresistance for non-small cell lung cancer (NSCLC) cells

Involvement of endothelial CK2 in the radiation induced perivascular resistant niche (PVRN) and the induction of radioresistance for non-small cell lung cancer (NSCLC) cells

Abstract Background Tumor microenvironment (TME) plays a vital role in determining the outcomes of radiotherapy. As an important component of TME, vascular endothelial cells are involved in the perivascular resistance niche (PVRN), which is formed by inflammation or cytokine production induced by io...

Full description

Bibliographic Details
Main Authors: Qianwen Li, Yan Zong, Ke Li, Xiaohua Jie, Jiaxin Hong, Xiaoshu Zhou, Bian Wu, Zhenyu Li, Sheng Zhang, Gang Wu, Rui Meng
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Biological Research
Subjects:
Protein kinase CK2
Ionizing radiation
Non-small cell lung cancer
NF-κB
Perivascular resistance niche (PVRN)
Online Access:http://link.springer.com/article/10.1186/s40659-019-0231-x

Internet

http://link.springer.com/article/10.1186/s40659-019-0231-x

Similar Items