Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity

Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity

The morphology and function of neuronal synapses are regulated by neural activity, as manifested in activity-dependent synapse maturation and various forms of synaptic plasticity. Here we employed cryo-electron tomography (cryo-ET) to visualize synaptic ultrastructure in cultured hippocampal neurons...

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Bibliographic Details
Main Authors: Chang-Lu Tao, Yun-Tao Liu, Z. Hong Zhou, Pak-Ming Lau, Guo-Qiang Bi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Neuroanatomy
Subjects:
synaptic structure
dense core vesicle
homeostatic plasticity
cryo-electron tomography
tetrodotoxin
Online Access:https://www.frontiersin.org/article/10.3389/fnana.2018.00048/full

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https://www.frontiersin.org/article/10.3389/fnana.2018.00048/full

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