SoxE group transcription factor Sox8 promotes astrocytic differentiation of neural stem/precursor cells downstream of Nfia

Abstract The brain consists of three major cell types: neurons and two glial cell types (astrocytes and oligodendrocytes). Although they are generated from common multipotent neural stem/precursor cells (NS/PCs), embryonic NS/PCs cannot generate all of the cell types at the beginning of brain develo...

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Bibliographic Details
Main Authors: Jun Takouda, Sayako Katada, Takuya Imamura, Tsukasa Sanosaka, Kinichi Nakashima
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.749