An Adjuvant Stem Cell Patch with Coronary Artery Bypass Graft Surgery Improves Diastolic Recovery in Porcine Hibernating Myocardium

An Adjuvant Stem Cell Patch with Coronary Artery Bypass Graft Surgery Improves Diastolic Recovery in Porcine Hibernating Myocardium

Diastolic dysfunction persists despite coronary artery bypass graft surgery (CABG) in patients with hibernating myocardium (HIB). We studied whether the adjunctive use of a mesenchymal stem cells (MSCs) patch during CABG improves diastolic function by reducing inflammation and fibrosis. HIB was indu...

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Bibliographic Details
Main Authors: Rishav Aggarwal, Koray N. Potel, Annie Shao, Simon W. So, Cory Swingen, Christina P. Reyes, Rebecca Rose, Christin Wright, Laura L. Hocum Stone, Edward O. McFalls, Tammy A. Butterick, Rosemary F. Kelly
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
hibernating myocardium
diastolic dysfunction
mesenchymal stem cell
ischemic heart disease
cardiac MRI
CABG
Online Access:https://www.mdpi.com/1422-0067/24/6/5475

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https://www.mdpi.com/1422-0067/24/6/5475

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