Crosstalk between β2- and α2-Adrenergic Receptors in the Regulation of B16F10 Melanoma Cell Proliferation

Crosstalk between β2- and α2-Adrenergic Receptors in the Regulation of B16F10 Melanoma Cell Proliferation

Adrenergic receptors (AR) belong to the G protein-coupled receptor superfamily and regulate migration and proliferation in various cell types. The objective of this study was to evaluate whether β-AR stimulation affects the antiproliferative action of α2-AR agonists on B16F10 cells and, if so, to de...

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Bibliographic Details
Main Authors: Paola Matarrese, Sonia Maccari, Barbara Ascione, Rosa Vona, Vanessa Vezzi, Tonino Stati, Maria Cristina Grò, Giuseppe Marano, Caterina Ambrosio, Paola Molinari
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
cyclic AMP
β2-adrenergic receptors
α2-adrenergic receptors
proliferation
melanoma
Online Access:https://www.mdpi.com/1422-0067/23/9/4634

Internet

https://www.mdpi.com/1422-0067/23/9/4634

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