3D in vitro M2 macrophage model to mimic modulation of tissue repair

Abstract Distinct anti-inflammatory macrophage (M2) subtypes, namely M2a and M2c, are reported to modulate the tissue repair process tightly and chronologically by modulating fibroblast differentiation state and functions. To establish a well-defined three-dimensional (3D) cell culture model to mimi...

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Bibliographic Details
Main Authors: Jiranuwat Sapudom, Shaza Karaman, Walaa K. E. Mohamed, Anna Garcia-Sabaté, Brian C. Quartey, Jeremy C. M. Teo
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00193-5