APOE E4 is associated with impaired self-declared cognition but not disease risk or age of onset in Nigerians with Parkinson’s disease

APOE E4 is associated with impaired self-declared cognition but not disease risk or age of onset in Nigerians with Parkinson’s disease

Abstract The relationship between APOE polymorphisms and Parkinson’s disease (PD) in black Africans has not been previously investigated. We evaluated the association between APOE polymorphic variability and self-declared cognition in 1100 Nigerians with PD and 1097 age-matched healthy controls. Cog...

Full description

Bibliographic Details
Main Authors: Njideka U. Okubadejo, Olaitan Okunoye, Oluwadamilola O. Ojo, Babawale Arabambi, Rufus O. Akinyemi, Godwin O. Osaigbovo, Sani A. Abubakar, Emmanuel U. Iwuozo, Kolawole W. Wahab, Osigwe P. Agabi, Uchechi Agulanna, Frank A. Imarhiagbe, Oladunni V. Abiodun, Charles O. Achoru, Akintunde A. Adebowale, Olaleye Adeniji, John E. Akpekpe, Mohammed W. Ali, Ifeyinwa Ani-Osheku, Ohwotemu Arigbodi, Salisu A. Balarabe, Abiodun H. Bello, Oluchi S. Ekenze, Cyril O. Erameh, Temitope H. Farombi, Michael B. Fawale, Morenikeji A. Komolafe, Paul O. Nwani, Ernest O. Nwazor, Yakub Nyandaiti, Emmanuel E. Obehighe, Yahaya O. Obiabo, Olanike A. Odeniyi, Francis E. Odiase, Francis I. Ojini, Gerald A. Onwuegbuzie, Nosakhare Osemwegie, Olajumoke O. Oshinaike, Folajimi M. Otubogun, Shyngle I. Oyakhire, Funlola T. Taiwo, Uduak E. Williams, Simon Ozomma, Yusuf Zubair, Dena Hernandez, Sara Bandres-Ciga, Cornelis Blauwendraat, Andrew Singleton, Henry Houlden, John Hardy, Mie Rizig
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00411-x

Internet

https://doi.org/10.1038/s41531-022-00411-x

Similar Items