Determination of the cycle threshold value of the Xpert Xpress SARS-CoV-2/Flu/RSV test that corresponds to the presence of infectious SARS-CoV-2 in anterior nasal swabs

Determination of the cycle threshold value of the Xpert Xpress SARS-CoV-2/Flu/RSV test that corresponds to the presence of infectious SARS-CoV-2 in anterior nasal swabs

ABSTRACTDespite having high analytical sensitivities and specificities, qualitative SARS-CoV-2 nucleic acid amplification tests (NAATs) cannot distinguish infectious from non-infectious virus in clinical samples. In this study, we determined the highest cycle threshold (Ct) value of the SARS-CoV-2 t...

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Bibliographic Details
Main Authors: Ryan F. Relich, Kayla Van Benten, Guang-Sheng Lei, Christopher M. Robinson, Mariel Carozza, Malaya K. Sahoo, ChunHong Huang, Daniel Solis, Mamdouh Sibai, Christopher A. Myers, Cynthia Sikorski, Caroline Balagot, David Yang, Benjamin A. Pinsky, Michael J. Loeffelholz
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
real-time reverse transcription PCR
cycle threshold (Ct) value
coronavirus
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03908-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03908-23

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