How can we consider variable RBE and LETd prediction during clinical practice? A pediatric case report at the Normandy Proton Therapy Centre using an independent dose engine

How can we consider variable RBE and LETd prediction during clinical practice? A pediatric case report at the Normandy Proton Therapy Centre using an independent dose engine

Abstract Background To develop an auxiliary GPU-accelerated proton therapy (PT) dose and LETd engine for the IBA Proteus®ONE PT system. A pediatric low-grade glioma case study is reported using FRoG during clinical practice, highlighting potential treatment planning insights using variable RBE dose...

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Bibliographic Details
Main Authors: Stewart Mein, Benedikt Kopp, Anthony Vela, Pauline Dutheil, Paul Lesueur, Dinu Stefan, Jürgen Debus, Thomas Haberer, Amir Abdollahi, Andrea Mairani, Thomas Tessonnier
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Radiation Oncology
Subjects:
Proton therapy
Dose calculation
LET
Treatment planning
GPU
Pediatrics
Online Access:https://doi.org/10.1186/s13014-021-01960-w

Internet

https://doi.org/10.1186/s13014-021-01960-w

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