Kupffer Cell Inactivation Alters Endothelial Cell Adhesion Molecules in Cecal Ligation and Puncture-Induced Sepsis

The activation of Kupffer cells, resident macrophages in the liver, is closely associated with the inflammatory response during sepsis, which leads to multiple-organ failure. However, how Kupffer cell activation affects adhesion molecules (ICAM-1 and VCAM-1) in sepsis has not been determined. This s...

Full description

Bibliographic Details
Main Authors: Sumeet Manandhar, Ravinder Reddy Gaddam, Stephen Chambers, Madhav Bhatia
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/14/1/84