Assessing a potential role of host Pannexin 1 during Chlamydia trachomatis infection.

Pannexin 1 (Panx1) is a plasma membrane channel glycoprotein that plays a role in innate immune response through association with the inflammasome complex. Probenecid, a classic pharmacological agent for gout, has also been used historically in combination therapy with antibiotics to prevent cellula...

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Bibliographic Details
Main Authors: Mary J McKuen, Gerhard Dahl, Kenneth A Fields
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3659042?pdf=render