Runx3 Restoration Regresses K-Ras-Activated Mouse Lung Cancers and Inhibits Recurrence

Runx3 Restoration Regresses K-Ras-Activated Mouse Lung Cancers and Inhibits Recurrence

Oncogenic <i>K-RAS</i> mutations occur in approximately 25% of human lung cancers and are most frequently found in codon 12 (G12C, G12V, and G12D). Mutated K-RAS inhibitors have shown beneficial results in many patients; however, the inhibitors specifically target K-RAS<i><sup&g...

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Bibliographic Details
Main Authors: Ja-Yeol Lee, Jung-Won Lee, Tae-Geun Park, Sang-Hyun Han, Seo-Yeong Yoo, Kyoung-Mi Jung, Da-Mi Kim, Ok-Jun Lee, Dohun Kim, Xin-Zi Chi, Eung-Gook Kim, You-Soub Lee, Suk-Chul Bae
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
runt-related transcription factor 3 (Runx3)
K-Ras
p53
lung cancer
resistance
recurrence
Online Access:https://www.mdpi.com/2073-4409/12/20/2438

Internet

https://www.mdpi.com/2073-4409/12/20/2438

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