Cannabinoid CB2 receptor ligands disrupt the sequential regulation of p-MEK1/2 to p-ERK1/2 in mouse brain cortex

Aim: The sequential phosphorylation of mitogen-activated protein (MAP) kinases MEK-ERK is the most relevant cellular signaling pathway. This study quantified the parallel in vivo regulation of brain phosphorylation-MEK1/2 (p-MEK1/2) to p-ERK1/2 by mechanistically different cannabinoid 2 (CB2) recept...

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Bibliographic Details
Main Authors: Glòria Salort, María Álvaro-Bartolomé, Jesús A. García-Sevilla
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-10-01
Series:Exploration of Neuroprotective Therapy
Subjects:
Online Access:https://www.explorationpub.com/Journals/ent/Article/100450