IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis
Abstract Atopic dermatitis (AD) is a common pruritic inflammatory skin disease with complex environmental and genetic predisposing factors. Primary skin barrier dysfunction and aberrant T helper 2 (TH2) responses to common allergens, together with increased serum IgE antibodies, characterise the dis...
Главные авторы: | , , , , , , |
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Формат: | Статья |
Язык: | English |
Опубликовано: |
Nature Portfolio
2023-01-01
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Серии: | Scientific Reports |
Online-ссылка: | https://doi.org/10.1038/s41598-022-26637-6 |