Differential effects of toluene and ethanol on dopaminergic neurons of the ventral tegmental area

Drugs of abuse increase the activity of dopaminergic neurons of the ventral tegmental area (VTA), and output from the VTA is critical for both natural and drug-induced reward and reinforcement. Ethanol and the abused inhalant toluene both enhance VTA neuronal firing, but the mechanisms of this effec...

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Bibliographic Details
Main Authors: Sudarat Nimitvilai, Chang You, Devinder Singh Arora, Maureen A. McElvain, Bertha J. Vandegrift, Mark S. Brodie, John J Woodward
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00434/full