Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.

INTRODUCTION: Stroma cells and extracellular matrix (ECM) components provide the pivotal microenvironment for tumor development. The study aimed to evaluate the importance of the pancreatic stroma for tumor development. METHODS: Pancreatic tumor cells were implanted subcutaneously into green fluores...

Full description

Bibliographic Details
Main Authors: Itai Spector, Yael Zilberstein, Adi Lavy, Arnon Nagler, Olga Genin, Mark Pines
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3404977?pdf=render