Epi-Impute: Single-Cell RNA-seq Imputation via Integration with Single-Cell ATAC-seq

Epi-Impute: Single-Cell RNA-seq Imputation via Integration with Single-Cell ATAC-seq

Single-cell RNA-seq data contains a lot of dropouts hampering downstream analyses due to the low number and inefficient capture of mRNAs in individual cells. Here, we present Epi-Impute, a computational method for dropout imputation by reconciling expression and epigenomic data. Epi-Impute leverages...

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Bibliographic Details
Main Authors: Mikhail Raevskiy, Vladislav Yanvarev, Sascha Jung, Antonio Del Sol, Yulia A. Medvedeva
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
single cell RNA-seq
imputation
single cell ATAC-seq
Online Access:https://www.mdpi.com/1422-0067/24/7/6229

Internet

https://www.mdpi.com/1422-0067/24/7/6229

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