VariantSurvival: a tool to identify genotype–treatment response

VariantSurvival: a tool to identify genotype–treatment response

Motivation: For a number of neurological diseases, such as Alzheimer’s disease, amyotrophic lateral sclerosis, and many others, certain genes are known to be involved in the disease mechanism. A common question is whether a structural variant in any such gene may be related to drug response in clini...

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Bibliographic Details
Main Authors: Thomas Krannich, Marina Herrera Sarrias, Hiba Ben Aribi, Moustafa Shokrof, Alfredo Iacoangeli, Ammar Al-Chalabi, Fritz J. Sedlazeck, Ben Busby, Ahmad Al Khleifat
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Bioinformatics
Subjects:
structural variants
survival analysis
clinical trials
personalized medicine
Kaplan–Meier
Cox regression
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2023.1277923/full

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https://www.frontiersin.org/articles/10.3389/fbinf.2023.1277923/full

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