A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models

A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models

Abstract SINE-VNTR-Alu (SVA) retrotransposons represent mobile regulatory elements that have the potential to influence the surrounding genome when they insert into a locus. Evolutionarily recent mobilisation has resulted in loci in the human genome where a given retrotransposon might be observed to...

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Bibliographic Details
Main Authors: Ashley Hall, Ben Middlehurst, Max A. M. Cadogan, Xylena Reed, Kimberley J. Billingsley, Vivien J. Bubb, John P. Quinn
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50307-w

Internet

https://doi.org/10.1038/s41598-023-50307-w

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