Mono and Multiple Tumor-Targeting Ligand-Coated Ultrasmall Gadolinium Oxide Nanoparticles: Enhanced Tumor Imaging and Blood Circulation

Mono and Multiple Tumor-Targeting Ligand-Coated Ultrasmall Gadolinium Oxide Nanoparticles: Enhanced Tumor Imaging and Blood Circulation

Hydrophilic and biocompatible PAA-coated ultrasmall Gd<sub>2</sub>O<sub>3</sub> nanoparticles (d<sub>avg</sub> = 1.7 nm) were synthesized and conjugated with tumor-targeting ligands, i.e., cyclic arginylglycylaspartic acid (cRGD) and/or folic acid (FA). FA-PAA-Gd&...

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Bibliographic Details
Main Authors: Son Long Ho, Huan Yue, Sangyeol Lee, Tirusew Tegafaw, Mohammad Yaseen Ahmad, Shuwen Liu, Abdullah Khamis Ali Al Saidi, Dejun Zhao, Ying Liu, Sung-Wook Nam, Kwon Seok Chae, Yongmin Chang, Gang Ho Lee
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
ultrasmall Gd<sub>2</sub>O<sub>3</sub> nanoparticle
folic acid
cRGD
multiple tumor-targeting ligand
tumor imaging
blood circulation enhancement
Online Access:https://www.mdpi.com/1999-4923/14/7/1458

Internet

https://www.mdpi.com/1999-4923/14/7/1458

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