Endogenous TRAIL-R4 critically impacts apoptotic and non-apoptotic TRAIL-induced signaling in cancer cells
Binding of TRAIL to its death domain-containing receptors TRAIL-R1 and TRAIL-R2 can induce cell death and/or pro-inflammatory signaling. The importance of TRAIL and TRAIL-R1/R2 in tumor immune surveillance and cancer biology has meanwhile been well documented. In addition, TRAIL has been shown to pr...
Asıl Yazarlar: | , , , , , , , |
---|---|
Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2022-09-01
|
Seri Bilgileri: | Frontiers in Cell and Developmental Biology |
Konular: | |
Online Erişim: | https://www.frontiersin.org/articles/10.3389/fcell.2022.942718/full |