Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage

Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage

Abstract Objective To investigate the occurrence and frequency of anti-citrullinated protein antibodies (ACPA) to cyclic citrullinated type II collagen (COL2) epitope with a capacity to bind joint cartilage. Methods Luminex immunoassay was used to analyze serum antibody reactivity to 10 COL2-citrull...

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Bibliographic Details
Main Authors: Qixing Li, Yanpeng Li, Bibo Liang, Rui Xu, Bingze Xu, Erik Lönnblom, Hui Feng, Jing’an Bai, Roma Stawikowska, Changrong Ge, Aiping Lu, Gregg B. Fields, Lianbo Xiao, Rikard Holmdahl
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Osteoarthritis
Anti-citrullinated type II collagen antibodies
Online Access:https://doi.org/10.1186/s13075-022-02945-0

Internet

https://doi.org/10.1186/s13075-022-02945-0

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