Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A (Sal A), extracted from Danshen, has proven efficacy in preventing cardiovascular diseases. However, its effect on mitigating vascular damage caused by chronic kidney disease remains unclear. This study investigated the therapeutic effects and underlying mechanisms of Sal A in a r...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Chengkai Wu, Bosai He, Xiao Wang, Yang Zou, Ruixin Ma, Yanting Gu, Jian Huang, Songping Li, Jinhui Wang, Jiahong Wang
Format: Article
Sprog:English
Udgivet: Elsevier 2023-11-01
Serier:Journal of Functional Foods
Fag:
Salvianolic acid A
Chronic kidney disease
Cardiovascular disease
Oxidative stress
Inflammation
Online adgang:http://www.sciencedirect.com/science/article/pii/S1756464623004619

Internet

http://www.sciencedirect.com/science/article/pii/S1756464623004619

Lignende værker