Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A (Sal A), extracted from Danshen, has proven efficacy in preventing cardiovascular diseases. However, its effect on mitigating vascular damage caused by chronic kidney disease remains unclear. This study investigated the therapeutic effects and underlying mechanisms of Sal A in a r...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Chengkai Wu, Bosai He, Xiao Wang, Yang Zou, Ruixin Ma, Yanting Gu, Jian Huang, Songping Li, Jinhui Wang, Jiahong Wang
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Elsevier 2023-11-01
Sraith:Journal of Functional Foods
Ábhair:
Salvianolic acid A
Chronic kidney disease
Cardiovascular disease
Oxidative stress
Inflammation
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S1756464623004619

Ar líne

http://www.sciencedirect.com/science/article/pii/S1756464623004619

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