Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A (Sal A), extracted from Danshen, has proven efficacy in preventing cardiovascular diseases. However, its effect on mitigating vascular damage caused by chronic kidney disease remains unclear. This study investigated the therapeutic effects and underlying mechanisms of Sal A in a r...

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Dettagli Bibliografici
Autori principali: Chengkai Wu, Bosai He, Xiao Wang, Yang Zou, Ruixin Ma, Yanting Gu, Jian Huang, Songping Li, Jinhui Wang, Jiahong Wang
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2023-11-01
Serie:Journal of Functional Foods
Soggetti:
Salvianolic acid A
Chronic kidney disease
Cardiovascular disease
Oxidative stress
Inflammation
Accesso online:http://www.sciencedirect.com/science/article/pii/S1756464623004619

Accesso online

http://www.sciencedirect.com/science/article/pii/S1756464623004619

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