Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A alleviates cardiovascular injury in rats with chronic kidney disease by activating the PI3K/Akt/Nrf2/HO-1 and SIRT1/TLR4/NF-κB/P38 signaling pathways

Salvianolic acid A (Sal A), extracted from Danshen, has proven efficacy in preventing cardiovascular diseases. However, its effect on mitigating vascular damage caused by chronic kidney disease remains unclear. This study investigated the therapeutic effects and underlying mechanisms of Sal A in a r...

Полное описание

Библиографические подробности
Главные авторы: Chengkai Wu, Bosai He, Xiao Wang, Yang Zou, Ruixin Ma, Yanting Gu, Jian Huang, Songping Li, Jinhui Wang, Jiahong Wang
Формат: Статья
Язык:English
Опубликовано: Elsevier 2023-11-01
Серии:Journal of Functional Foods
Предметы:
Salvianolic acid A
Chronic kidney disease
Cardiovascular disease
Oxidative stress
Inflammation
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1756464623004619

Internet

http://www.sciencedirect.com/science/article/pii/S1756464623004619

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