Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2.

BACKGROUND: HMGA2 is an architectonic transcription factor abundantly expressed during embryonic and fetal development and it is associated with the progression of malignant tumors. The protein harbours three basically charged DNA binding domains and an acidic protein binding C-terminal domain. DNA...

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Bibliographic Details
Main Authors: Nina Winter, Rolf Nimzyk, Carolin Bösche, Anke Meyer, Jörn Bullerdiek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3077414?pdf=render