Transcriptomic profile of TNFhigh MAIT cells is linked to B cell response following SARS-CoV-2 vaccination

Transcriptomic profile of TNFhigh MAIT cells is linked to B cell response following SARS-CoV-2 vaccination

IntroductionHigher frequencies of mucosal-associated invariant T (MAIT) cells were associated with an increased adaptive response to mRNA BNT162b2 SARS-CoV-2 vaccine, however, the mechanistic insights into this relationship are unknown. In the present study, we hypothesized that the TNF response of...

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Bibliographic Details
Main Authors: Paolo Marzano, Simone Balin, Sara Terzoli, Silvia Della Bella, Valentina Cazzetta, Rocco Piazza, Inga Sandrock, Sarina Ravens, Likai Tan, Immo Prinz, Francesca Calcaterra, Clara Di Vito, Assunta Cancellara, Michela Calvi, Anna Carletti, Sara Franzese, Alessandro Frigo, Ahmed Darwish, Antonio Voza, Joanna Mikulak, Domenico Mavilio
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
mRNA vaccine
MAIT cells
immune response
TNF
B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1208662/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1208662/full

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