Ellagic acid and cilostazol ameliorate amikacin-induced nephrotoxicity in rats by downregulating oxidative stress, inflammation, and apoptosis

Amikacin (AK) has the largest spectrum of aminoglycosides. However, its use is constrained because of nephrotoxicity and ototoxicity. Ellagic acid (EA) is a polyphenol present in plants. It has antioxidant, anticarcinogenic, and antimutagenic characteristics. Cilostazol (CTZ) is a phosphodiesterase...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Zeinab Mahmoud Saeed, Monira Ismail Khattab, Nadia Esmat Khorshid, Amal Elsayed Salem
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2022-01-01
Sraith:PLoS ONE
Rochtain ar líne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292089/?tool=EBI