Shellfish Toxins Targeting Voltage-Gated Sodium Channels

Voltage-gated sodium channels (VGSCs) play a central role in the generation and propagation of action potentials in excitable neurons and other cells and are targeted by commonly used local anesthetics, antiarrhythmics, and anticonvulsants. They are also common targets of neurotoxins including shell...

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Bibliographic Details
Main Authors: Fan Zhang, Xunxun Xu, Tingting Li, Zhonghua Liu
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/12/4698