<i>ICOS</i> Gene Polymorphisms (IVS1 + 173 T/C and c. 1624 C/T) in Primary Sjögren’s Syndrome Patients: Analysis of ICOS Expression

<i>ICOS</i> Gene Polymorphisms (IVS1 + 173 T/C and c. 1624 C/T) in Primary Sjögren’s Syndrome Patients: Analysis of ICOS Expression

Background: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease, which affects exocrine glands. T cell activation is a trigger mechanism in the immune response. Hyperreactivity of T cells and antibody production are features in pSS. ICOS can be critical in the pathogenesis of pSS. Meth...

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Bibliographic Details
Main Authors: José Antonio García-Espinoza, José Francisco Muñoz-Valle, Mariel García-Chagollán, Jorge Hernández-Bello, Claudia Azucena Palafox-Sánchez, Erika Fabiola López-Villalobos, Gabriela Athziri Sánchez-Zuno, Gloria Esther Martínez-Bonilla, Sergio Cerpa-Cruz, Francisco Josue Carrillo-Ballesteros, Edith Oregon-Romero
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Current Issues in Molecular Biology
Subjects:
ICOS
polymorphism
primary Sjögren’s syndrome
autoimmune diseases
Online Access:https://www.mdpi.com/1467-3045/44/2/53

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https://www.mdpi.com/1467-3045/44/2/53

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