Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1

Abstract Background Osteosarcoma (OS) is the most frequent cancer derived from bone, and the prognosis of OS is poor. Metabolic alterations have been previously reported to contribute to the development of OS, and arsenic compounds have been suggested to exhibit strong anti-OS effects. However, few...

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Détails bibliographiques
Auteurs principaux: Yixin Liu, Wenyan She, Yi Li, Miao Wang, Yin Liu, Biao Ning, Tianzi Xu, Tianhe Huang, Yongchang Wei
Format: Article
Langue:English
Publié: BMC 2023-01-01
Collection:Journal of Translational Medicine
Sujets:
Accès en ligne:https://doi.org/10.1186/s12967-022-03862-1