Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1

Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1

Abstract Background Osteosarcoma (OS) is the most frequent cancer derived from bone, and the prognosis of OS is poor. Metabolic alterations have been previously reported to contribute to the development of OS, and arsenic compounds have been suggested to exhibit strong anti-OS effects. However, few...

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Bibliographic Details
Main Authors: Yixin Liu, Wenyan She, Yi Li, Miao Wang, Yin Liu, Biao Ning, Tianzi Xu, Tianhe Huang, Yongchang Wei
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Translational Medicine
Subjects:
Osteosarcoma
Arsenic
ROS
Apoptosis
PDK-1
Online Access:https://doi.org/10.1186/s12967-022-03862-1

Internet

https://doi.org/10.1186/s12967-022-03862-1

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