Endoplasmic reticulum stress in melanoma pathogenesis and resistance

Endoplasmic reticulum stress in melanoma pathogenesis and resistance

Melanoma is the most lethal skin cancer with rising incidence worldwide. Despite significant advances in target therapy and immunotherapy, low response rates and the development of drug resistance remain key clinical barriers affecting patient prognosis. The complex interplay between multiple signal...

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Bibliographic Details
Main Authors: Yi Kong, Jian Jiang, Yuqiong Huang, Li Li, Xin Liu, Zilin Jin, Fen Wei, Xinxin Liu, Song Zhang, Xiaoru Duan, Yonghui Zhang, Qingyi Tong, Hongxiang Chen
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Melanoma
ER stress
UPR
IRE1
PERK
ATF6
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222011301

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http://www.sciencedirect.com/science/article/pii/S0753332222011301

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