Full-spectral genome analysis of natural killer/T cell lymphoma highlights impacts of genome instability in driving its progression

Full-spectral genome analysis of natural killer/T cell lymphoma highlights impacts of genome instability in driving its progression

Abstract Background Natural killer/T cell lymphoma (NKTCL) is a clinically and genetically heterogeneous disease with poor prognosis. Genome sequencing and mutation characterization provides a powerful approach for patient stratification, treatment target discovery, and etiology identification. Howe...

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Bibliographic Details
Main Authors: Zegeng Chen, He Huang, Huangming Hong, Huageng Huang, Huawei Weng, Le Yu, Jian Xiao, Zhao Wang, Xiaojie Fang, Yuyi Yao, Jia-Xing Yue, Tongyu Lin
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Genome Medicine
Subjects:
Natural killer/T cell lymphoma
Genomic alteration
Genome instability
Chromothripsis
Molecular subtypes
Online Access:https://doi.org/10.1186/s13073-024-01324-5

Internet

https://doi.org/10.1186/s13073-024-01324-5

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