Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing.

Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing.

Capsaicin-sensitive sensory C-fibers derived from vagal ganglia innervate the visceral organs, and respond to inflammatory mediators and noxious stimuli. These neurons play an important role in maintenance of visceral homeostasis, and contribute to the symptoms of visceral inflammatory diseases. Vag...

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Bibliographic Details
Main Authors: Jingya Wang, Marian Kollarik, Fei Ru, Hui Sun, Benjamin McNeil, Xinzhong Dong, Geoffrey Stephens, Susana Korolevich, Philip Brohawn, Roland Kolbeck, Bradley Undem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5628920?pdf=render

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http://europepmc.org/articles/PMC5628920?pdf=render

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