Molecular Structural Analysis of Porcine CMAH–Native Ligand Complex and High Throughput Virtual Screening to Identify Novel Inhibitors

Porcine meat is the most consumed red meat worldwide. Pigs are also vital tools in biological and medical research. However, xenoreactivity between porcine’s N-glycolylneuraminic acid (Neu5Gc) and human anti-Neu5Gc antibodies poses a significant challenge. On the one hand, dietary Neu5Gc intake has...

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Bibliographic Details
Main Authors: Oluwamayowa Joshua Ogun, Georg Thaller, Doreen Becker
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/12/5/684