High-dose chemotherapy sensitizes locally advanced esophageal squamous cell carcinoma to PD-1 blockade for a higher pathological complete response rate and survival

High-dose chemotherapy sensitizes locally advanced esophageal squamous cell carcinoma to PD-1 blockade for a higher pathological complete response rate and survival

Background: PD-1 inhibitor and chemotherapy demonstrated durable antitumor activity with a manageable safety profile as the first-line treatment in patients with advanced esophageal squamous cell carcinoma (ESCC). The present study aimed to evaluate the efficacy of PD-1 inhibitors plus different dos...

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Bibliographic Details
Main Authors: Peiyuan Wang, Mengxia Lei, Guibin Weng, Rongfang Huang, Hui Lin, Wenwei Wei, Yujie Chen, Hao He, Peng Chen, Derong Zhang, Weijie Chen, Hang Zhou, Pengqiang Gao, Shuoyan Liu, Feng Wang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Translational Oncology
Subjects:
Locally advanced esophageal squamous cell carcinoma
Neoadjuvant chemotherapy
PD-1 inhibitor
Dose intensity
Efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323001225

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http://www.sciencedirect.com/science/article/pii/S1936523323001225

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