Topical Meloxicam Hydroxypropyl Guar Hydrogels Based on Low-Substituted Hydroxypropyl Cellulose Solid Dispersions

Topical Meloxicam Hydroxypropyl Guar Hydrogels Based on Low-Substituted Hydroxypropyl Cellulose Solid Dispersions

Meloxicam (MX) is a poorly water-soluble drug with severe gastrointestinal side effects. Topical hydrogel of hydroxypropyl guar (HPG) was formulated using a solid dispersion (SD) of MX with hydroxypropyl cellulose (LHPC) as an alternative to oral administration. The development of a solid dispersion...

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Bibliographic Details
Main Authors: Zaid Dahma, Carlos Torrado-Salmerón, Covadonga Álvarez-Álvarez, Víctor Guarnizo-Herrero, Borja Martínez-Alonso, Guillermo Torrado, Santiago Torrado-Santiago, Paloma Marina de la Torre-Iglesias
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Gels
Subjects:
meloxicam
low-substituted hydroxypropyl cellulose
hydroxypropyl guar
solid dispersion
hydrogels
polymer/polymer interactions
Online Access:https://www.mdpi.com/2310-2861/10/3/207

Internet

https://www.mdpi.com/2310-2861/10/3/207

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