Design, preparation, and in vitro evaluation of gastroretentive floating matrix tablet of mitiglinide

Design, preparation, and in vitro evaluation of gastroretentive floating matrix tablet of mitiglinide

The present research is focused on developing floating matrix tablets of mitiglinide to prolong its gastric residence time for better absorption. Gastroretentive tablets were prepared using a direct compression technique with hydroxypropyl methylcellulose K15M (HPMC K15M) and sodium alginate as matr...

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Bibliographic Details
Main Authors: Meenakshi Patel, Santosh Shelke, Naazneen Surti, Prabhakar Panzade, Lamya Ahmed Al-Keridis, Tarun Kumar Upadhyay, Nawaf Alshammari, Mohd Saeed
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
floating matrix tablet
mitiglinide
gastroretentive
radiography
factorial design
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1140351/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1140351/full

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