Design, preparation, and in vitro evaluation of gastroretentive floating matrix tablet of mitiglinide

The present research is focused on developing floating matrix tablets of mitiglinide to prolong its gastric residence time for better absorption. Gastroretentive tablets were prepared using a direct compression technique with hydroxypropyl methylcellulose K15M (HPMC K15M) and sodium alginate as matr...

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Main Authors: Meenakshi Patel, Santosh Shelke, Naazneen Surti, Prabhakar Panzade, Lamya Ahmed Al-Keridis, Tarun Kumar Upadhyay, Nawaf Alshammari, Mohd Saeed
格式: 文件
语言:English
出版: Frontiers Media S.A. 2023-03-01
丛编:Frontiers in Pharmacology
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在线阅读:https://www.frontiersin.org/articles/10.3389/fphar.2023.1140351/full