Differential upregulation of AU-rich element-containing mRNAs in COVID-19

Abstract Background AU-rich elements (AREs) are located in the 3′UTRs of 22% of human mRNAs, including most transiently expressed inflammatory mediators. By default, AREs mark mRNAs for decay and translational inhibition, but this activity can be temporarily inhibited in case of infection to allow t...

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Bibliographic Details
Main Authors: Tala Bakheet, Khalid S. A. Khabar, Edward G. Hitti
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-022-00433-9