A combined high-throughput and high-content platform for unified on-chip synthesis, characterization and biological screening

On-chip synthesis and screening has been used to automate drug discovery but on-chip analysis still remains a major limitation. Here, the authors report on a dendrimer-based surface patterning method to create nanodroplet arrays on materials which allow for on-chip high-throughput analysis.

Bibliographic Details
Main Authors: Maximilian Benz, Arndt Asperger, Meike Hamester, Alexander Welle, Stefan Heissler, Pavel A. Levkin
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19040-0