Human pluripotent stem cell (hPSC)-derived microglia for the study of brain disorders. A comprehensive review of existing protocols
Microglia, resident immune cells of the brain that originate from the yolk sac, play a critical role in maintaining brain homeostasis by monitoring and phagocytosing pathogens and cellular debris in the central nervous system (CNS). While they share characteristics with myeloid cells, they are disti...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-06-01
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Series: | IBRO Neuroscience Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667242124000290 |