Human pluripotent stem cell (hPSC)-derived microglia for the study of brain disorders. A comprehensive review of existing protocols

Microglia, resident immune cells of the brain that originate from the yolk sac, play a critical role in maintaining brain homeostasis by monitoring and phagocytosing pathogens and cellular debris in the central nervous system (CNS). While they share characteristics with myeloid cells, they are disti...

Full description

Bibliographic Details
Main Authors: Fionicca Teo, Catherine Yen Li Kok, Mao-Jia Tan, H. Shawn Je
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:IBRO Neuroscience Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242124000290