Human pluripotent stem cell (hPSC)-derived microglia for the study of brain disorders. A comprehensive review of existing protocols

Human pluripotent stem cell (hPSC)-derived microglia for the study of brain disorders. A comprehensive review of existing protocols

Microglia, resident immune cells of the brain that originate from the yolk sac, play a critical role in maintaining brain homeostasis by monitoring and phagocytosing pathogens and cellular debris in the central nervous system (CNS). While they share characteristics with myeloid cells, they are disti...

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Bibliographic Details
Main Authors:	Fionicca Teo, Catherine Yen Li Kok, Mao-Jia Tan, H. Shawn Je
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Series:	IBRO Neuroscience Reports
Subjects:	Human pluripotent stem cells Microglia Classical differentiation Organoid Directed differentiation Neurodegenerative diseases
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667242124000290

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