Alzheimer’s Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila
Alzheimer’s disease (AD) is the most common form of dementia and is characterized by intracellular neurofibrillary tangles of hyperphosphorylated Tau, including the 0N4R isoform and accumulation of extracellular amyloid beta (Aβ) plaques. However, less than 5% of AD cases are familial, with many add...
| Main Authors: | , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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Frontiers Media S.A.
2019-06-01
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| 丛编: | Frontiers in Cellular Neuroscience |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/article/10.3389/fncel.2019.00260/full |