LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target

LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target

Abstract Background Novel biomarkers are required to discern between breast tumors that should be targeted for treatment from those that would never become clinically apparent and/or life threatening for patients. Moreover, therapeutics that specifically target breast cancer (BC) cells with tumor-in...

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Bibliographic Details
Main Authors: Catharina Hagerling, Mark Owyong, Vaishnavi Sitarama, Chih-Yang Wang, Charlene Lin, Renske J. E. van den Bijgaart, Charlotte D. Koopman, Audrey Brenot, Ankitha Nanjaraj, Fredrik Wärnberg, Karin Jirström, Ophir D. Klein, Zena Werb, Vicki Plaks
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Cancer
Subjects:
LGR5
Breast cancer
DCIS
Estrogen receptor
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s12885-020-06986-z

Internet

http://link.springer.com/article/10.1186/s12885-020-06986-z

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