Systems level identification of a matrisome-associated macrophage polarisation state in multi-organ fibrosis

Tissue fibrosis affects multiple organs and involves a master-regulatory role of macrophages which respond to an initial inflammatory insult common in all forms of fibrosis. The recently unravelled multi-organ heterogeneity of macrophages in healthy and fibrotic human disease suggests that macrophag...

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Bibliographic Details
Main Authors: John F Ouyang, Kunal Mishra, Yi Xie, Harry Park, Kevin Y Huang, Enrico Petretto, Jacques Behmoaras
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/85530